ABSTRACT
Febrile seizures is one of the most common neurological diseases in childhood and the most common reason of convulsions. Although most of the convulsions have a good prognosis, prolonged febrile seizures can lead to hypoxic ischemic brain injury and influence the long-term intellectual development if the convulsions are repeated. It will lead to cognitive abilities, learning and memory decline, and even become the pathophysiological etiology of intractable epilepsy. Therefore,it has been became a great concern due to its serious impact on the quality of the child′s life. How to safely and effectively prevent the onset of febrile seizures has been an important task in pediatric clinical work. At present,there are some variously pre-ventive treatment guidelines or specifications,but it still left a debate about its effect. This article reviewed the progress of the studies on the preventive treatment of febrile seizures,so as to improve the understanding and the level of clinical preventive treatment of febrile seizures of the pediatricians.
ABSTRACT
Objective To evaluate clinical effect of Compound Fanshiliu Recipe(CFR) for the treatment of over-weighted type 2 diabetes mellitus(T2DM). Methods One hundred and twenty over-weighted T2DM patients were randomized into treatment group and control group, 60 cases in each group. Both groups were given oral use of Metformin Hydrochloride Enteric-Coated Tablets, and additionally the treatment group was treated with CFR orally. The treatment of both groups lasted for 12 continuous weeks. Before and after treatment, we detected the waist circumference (WC), body mass index (BMI), and the levels of fasting blood glucose(FBG), postprandial 2-hour blood glucose(P2hBG), glycosylated hemoglobin(HbA1c), total cholesterol(TC), triglyceride (TG), and free fatty acid (FFA). The therapeutic effect of the two groups was also evaluated after treatment. Results (1) The total effective rate for traditional Chinese medical symptoms was 95.00% in the treatment group, and was 70.00%in the control group, the difference being significant(P0.05). The decrease of WC and BMI of the treatment group was superior to that of the control group(P<0.05).(3) After treatment, levels of FBG, P2hBG, HbA1c, TC, TG, and FFA of both groups were significantly improved (P<0.05), and the improvement of the treatment group was superior to that of the control group(P<0.05).(4) Three patients of the treatment group suffered from slight gastric discomfort, and the discomfort was relieved without any special treatment. Other patients of the two groups had no adverse reaction. Conclusion Treatment of CFR combined with Metformin has been proved to be an effective and safe approach to decrease blood glucose and blood lipid levels, promote weight loss, and ameliorate traditional Chinese medical symptoms.